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Diabetic foot ulcers. Where we are and where are we going?

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Acta Endo Buc 1 2 : doi: The burden of diabetic foot ulcers. Pathways to diabetic limb amputation.

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Basis for prevention. Diabetes Care ; 13 5 Graftskin, a human skin equivalent, is effective in the nagement of noninfected neuropathic diabetic foot ulcers: a prospective randomized multicenter clinical trial.

Diabetes Care ; 24 2 Neuroendocrine cancer blurred vision of dermagraft, a cultured human dermis, to treat diabetic foot ulcers. Diabetes Care ; 19 4 Growth factors in the treatment of diabetic foot ulcers.

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Br J Surg ; 90 2 Efficacy and safety of becaplermin recombinant human platelet-derived growth factor-BB in patients with nonhealing, lower extremity diabetic ulcers: a combined analysis of four randomize [CrossRef] 7. Extravasation of macromolecules and possible trapping of transforming growth factor-beta in venous ulceration.

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Br J Dermatol ; 1 Analysis of the acute and chronic wound environments: the role of proteases and their inhibitors. Wound Repair Regen ; 7 6 Insulin-like growth factor-I receptor activity is essential for Kaposi?

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Br J Cancer ; 92 8 Nat Med ; 9 5 Inhibited proliferation of fibroblasts derived from chronic diabetic wounds and normal dermal fibroblasts treated with high glucose is associated with increased formation of l-lactate. Wound Repair Regen [CrossRef] Eur J Cell Biol ; 81 3 Hehenberger K, Hansson A.

High glucose-induced growth factor resistance in human fibroblasts can be reversed by antioxidants and protein kinase C-inhibitors.

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Cell Biochem Funct ; 15 3 Vascular factors and metabolic interactions in the pathogenesis of diabetic neuropathy. Diabetologia ; 44 11 Hyperglycemic pseudohypoxia and diabetic complications.

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Diabetes ; 42 6 Transcutaneous oxygen tension and toe blood pressure as predictors for outcome of diabetic foot ulcers. Diabetes Care ; 22 1 Sarcoma cancer lesions prospective evaluation of transcutaneous oxygen measurements in the management of diabetic foot problems. J Vasc Surg ; 22 4 Hyperbaric oxygen HBO therapy in treatment of diabetic foot ulcers.

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Long-term follow-up. J Diabetes Complications ; 16 2 Neuroendocrine cancer blurred vision review of hyperbaric oxygen in the management of chronic wounds. Br J Surg ; 92 neuroendocrine cancer blurred vision Hypoxia promotes fibrogenesis in human renal fibroblasts.

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Kidney Int ; 58 6 Hypoxia increases human keratinocyte motility on connective tissue. J Clin Invest ; 11 Cellular dysfunction in the diabetic fibroblast: impairment in migration, vascular endothelial growth factor production, and response to hypoxia.

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Am J Pathol ; 1 Hyperglycemia regulates hypoxiainducible factor-1alpha protein stability and function. Diabetes ; 53 12 Induction of hypervascularity without leakage or inflammation in transgenic mice overexpressing hypoxiainducible factor-1alpha. Genes Dev ; 15 19 Accelerated diabetic wound healing using cultured dermal fibroblasts retrovirally transduced with the platelet-derived growth factor B gene. Ann Plast Surg ; 51 4 Crombleholme TM.

ACTA ENDOCRINOLOGICA (BUC)

Adenoviral-mediated gene transfer in wound healing. Wound Repair Regen ; 8 6 J Invest Dermatol ; 4 Clinical protocol: Phase I trial to evaluate the safety of H5. PDGF-B for the treatment of a diabetic insensate foot ulcer. J Vasc Res ; 40 4